Gateway Cloning Technology

Automated protein production by cloning techniques is a bottleneck for many crystallography groups and in protein research in general. HAMILTON provides a fully automated solution for Invitrogen's Gateway® Cloning Technology which also can be integrated into our crystallization systems. The Cloning System for Gateway® Technology allows performance of all steps relevant to the cloning process starting from PCR products, including LR and BP reactions, PCR setups and cycling, plasmid preps, quality control steps (E-gel or off-line sequencing), colony picking on the same instrument and archiving of clones. The system has built-in data tracking: the status of PCR products can be tracked throughout the entire process including image information from colony picking and quality control (if available).